ENO1 Recombinant monoclonal antibody proteintech 81478-1-RR

$449.00
In stock
SKU
81478-1-RR

 

ENO1L1, EC:4.2.1.11, C-myc promoter-binding protein, Alpha-enolase, 2-phospho-D-glycerate hydro-lyase

Host / Isotype: Rabbit / IgG Class: Antibody
Reactivity: human, mouse, rat, pig Immunogen: enolase 1, (alpha)
 Applications: WB, IHC, IF/ICC, ELISA Observed Molecular Weight: 47 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: ENO1
Conjugate: Unconjugated Gene Symbol: 2023
Tested Applications: Positive WB detected in Gene ID (NCBI): ENSG00000074800
Application: Western Blot (WB) RRID: AB_2935553
Dilution: WB : 1:5000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat, Pig Form: Liquid
Host / Isotype: Recombinant Background Information: ENO1, also named as NNE, ENO1L1, MBPB1, MPB1 and MBP1, belongs to the enolase family. ENO1 is a metabolic enzyme involved in the synthesis of pyruvate. It also acts as a plasminogen receptor and mediates the activation of plasmin and extracellular matrix degradation. In tumor cells, ENO1 is up-regulated and supports the Warburg effect; it is expressed at the cell surface, where it promotes cancer invasion, and is subjected to a specific array of post-translational modifications, namely acetylation, methylation and phosphorylation. ENO1 overexpression and post-translational modifications could be of diagnostic and prognostic value in many cancer types. (PMID: 27814656). This antibody is specific to ENO1 and has no cross-reaction with ENO2 and ENO3.

 

 

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