AGER/RAGE Recombinant monoclonal antibody proteintech 83759-4-RR
$449.00
In stock
SKU
83759-4-RR
RAGE, AGER, Advanced glycosylation end product-specific receptor, 240706F7
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: rat | Immunogen: advanced glycosylation end product-specific receptor |
| Applications: WB, IF-P, ELISA | Observed Molecular Weight: 45 kDa, 58 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: 81722 |
| Conjugate: Unconjugated | Gene Symbol: AB_3671354 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): Unconjugated |
| Application: Western Blot (WB) | RRID: Liquid |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Protein A purfication |
| Tested Reactivity: Rat | Form: Q63495 |
| Host / Isotype: Recombinant | Background Information: Advanced glycosylation end product-specific receptor (AGER, also known as RAGE) is a member of the immunoglobulin superfamily of cell surface receptors, which interacts with distinct families of ligands, mediating diverse functions in a broad array of cell types including cellular migration, proliferation, survival and apoptosis (PMID: 12645002; 17425919). It senses endogenous stress signals with a broad ligand repertoire including advanced glycation end products, S100 proteins, high-mobility group box 1 protein/HMGB1, amyloid beta/APP oligomers, nucleic acids, phospholipids and glycosaminoglycans (PMID: 19910580; 28627626). It interacts with distinct molecules implicated in homeostasis, development, inflammation, and certain diseases such as diabetes and Alzheimer's disease (PMID: 26253613; 31079281). |
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