Endoglin/CD105 Recombinant monoclonal antibody proteintech 82993-6-RR
$449.00
In stock
SKU
82993-6-RR
CD105, 241196G9, HHT1, ENG, Endoglin
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: endoglin |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 75-90 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: CD105 |
| Conjugate: Unconjugated | Gene Symbol: 2022 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3670742 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481) |
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