DARS2 Recombinant monoclonal antibody proteintech 85691-2-RR

$449.00
In stock
SKU
85691-2-RR

 

Aspartate? tRNA ligase, Aspartate--tRNA ligase, mitochondrial, Aspartyl-tRNA synthetase, AspRS, EC:6.1.1.12

Host / Isotype: Rabbit / IgG Class: Antibody
Reactivity: human, mouse Immunogen: aspartyl-tRNA synthetase 2, mitochondrial
 Applications: WB, IF/ICC, ELISA Observed Molecular Weight: 66-74 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: DARS2
Conjugate: Unconjugated Gene Symbol: 55157
Tested Applications: Positive WB detected in Gene ID (NCBI): Unconjugated
Application: Western Blot (WB) RRID: Liquid
Dilution: WB : 1:5000-1:50000 Conjugate: Protein A purification
Tested Reactivity: Human, Mouse Form: Q6PI48
Host / Isotype: Recombinant Background Information: DARS2 is also named as AspRS (aspartyl-tRNA synthetase) and belongs to the class-II aminoacyl-tRNA synthetase family. The deduced 645-amino acid protein has a 47-amino acid mitochondrial targeting signal, resulting in a mature protein of 598 amino acids. DARS2 contains conserved residues involved in ATP binding, tRNA binding, and aspartic acid recognition, as well as catalytic site motifs characteristic of amino acid tRNA synthetases. It is a dimeric proteins(PMID:19443655). Rat aspartyl-tRNA synthetase has a N-terminal polypeptide extension of about 40 amino acid residues which can be removed without impairing its catalytic activity(PMID:9030747). This protein has different molecular mass(55 kDa, 50 kDa,66 kDa ) according to the publications(PMID:11306575; 19443655;15299749).

 

 

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