Cytokeratin 14 Recombinant monoclonal antibody proteintech 82824-1-RR
$449.00
In stock
SKU
82824-1-RR
KRT14, 1L19, CK 14, CK14, CK-14
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: keratin 14 |
| Applications: WB, IF/ICC, ELISA | Observed Molecular Weight: 52 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: Cytokeratin 14 |
| Conjugate: Unconjugated | Gene Symbol: 3861 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3086548 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:12000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: Cytokeratin 14, one of about 20 different cytokeratin isotypes of human cells, is the intermediate filament protein characteristic of epithelial cells. Cytokeratin 14 is expressed in the basal compartment of all stratified squamous epithelia. In various kinds of human tumors, the appearance and increasing expression of Cytokeratin 14 were strikingly associated with higher grade and stage of carcinoma, with varying degrees of unfavorable prognosis. In lung squamous cell carcinoma(LSCC), Cytokeratin 14 was expressed in the tumor cell nests showing stromal invasion with fibrosis and lymph node metastases, indicating that Cytokeratin 14 involved in proliferation and metastasis of LSCC. Cytokeratin 14 expression is sometimes used in diagnosis of myoepithelioma1 and intraductal vs. invasive ductal carcinoma of the breast. |
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