Coilin Recombinant monoclonal antibody proteintech 87171-1-RR

$449.00
In stock
SKU
87171-1-RR

 

COIL, CLN80, p80 coilin, p80-coilin

Host / Isotype: Rabbit / IgG Class: Antibody
Reactivity: human, mouse, rat Immunogen: coilin
 Applications: WB, IF/ICC, ELISA Observed Molecular Weight: 75 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: COIL
Conjugate: Unconjugated Gene Symbol: 8161
Tested Applications: Positive WB detected in Gene ID (NCBI): Unconjugated
Application: Western Blot (WB) RRID: Liquid
Dilution: WB : 1:5000-1:50000 Conjugate: Protein A purification
Tested Reactivity: Human, Mouse, Rat Form: P38432
Host / Isotype: Recombinant Background Information: The nuclear coiled body(CBs) and nuclear structures known as gems contain high concentrations of the survival motor neurons (SMN) protein complex. CBs and gems often colocalize, and communication between them is mediated by COIL. COIL is a component of the CBS which are involved in the function or assembly/disassembly of nucleoplasmic snRNPs. During mitosis, CBs disassemble, coinciding with a mitotic-specific phosphorylation of p80 coilin, and symmetrical dimethylation of the COIL RG box motif is a molecular switch that determines whether the SMN complex forms gems or becomes incorporated into CBs.

 

 

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