Coilin Recombinant monoclonal antibody proteintech 87171-1-RR
$449.00
In stock
SKU
87171-1-RR
COIL, CLN80, p80 coilin, p80-coilin
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: coilin |
| Applications: WB, IF/ICC, ELISA | Observed Molecular Weight: 75 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: COIL |
| Conjugate: Unconjugated | Gene Symbol: 8161 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): Unconjugated |
| Application: Western Blot (WB) | RRID: Liquid |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Protein A purification |
| Tested Reactivity: Human, Mouse, Rat | Form: P38432 |
| Host / Isotype: Recombinant | Background Information: The nuclear coiled body(CBs) and nuclear structures known as gems contain high concentrations of the survival motor neurons (SMN) protein complex. CBs and gems often colocalize, and communication between them is mediated by COIL. COIL is a component of the CBS which are involved in the function or assembly/disassembly of nucleoplasmic snRNPs. During mitosis, CBs disassemble, coinciding with a mitotic-specific phosphorylation of p80 coilin, and symmetrical dimethylation of the COIL RG box motif is a molecular switch that determines whether the SMN complex forms gems or becomes incorporated into CBs. |