TOP2A-Specific Polyclonal antibody proteintech 20233-1-AP
$449.00
In stock
SKU
20233-1-AP
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human And More (1) | Immunogen: Peptide Predict reactive species |
| Applications: WB, IHC, IF/ICC, IP, ELISA | Observed Molecular Weight: 174 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_001067 |
| Conjugate: Unconjugated | Gene Symbol: TOP2A |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 7153 |
| Application: Western Blot (WB) | RRID: AB_10664923 |
| Dilution: WB : 1:2000-1:16000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: TOP2A, also named as TOP2, belongs to the type II topoisomerase family. Topoisomerase II makes double-strand breaks. TOP2 control the topological states of DNA by transient breakage and subsequent rejoining of DNA strands. TOP2A may play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation. DNA topoisomerase IIa (170 kDa, TOP2a/170) is essential in proliferating cells by resolving DNA topological entanglements during chromosome condensation, replication, and segregation. |
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