Chk1 Recombinant monoclonal antibody proteintech 80056-2-RR
$449.00
In stock
SKU
80056-2-RR
CHEK1, 2G7, Checkpoint kinase-1, CHEK 1, Chk 1
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: CHK1 checkpoint homolog (S. pombe) |
| Applications: WB, IF/ICC, ELISA | Observed Molecular Weight: 55 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: Chk1 |
| Conjugate: Unconjugated | Gene Symbol: 1111 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3670463 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: CHEK1(Checkpoint kinase-1) is also named as CHK1 and belongs to the protein kinase superfamily. It is implicated in a circuit in which it activates checkpoints, DNA repair and proliferating cell nuclear antigen and FANCD2 monoubiquitinylation(PMID:21389083). CHEK1 protects vertebrate cells against spontaneous chromosome missegregation and is required to sustain anaphase delay when spindle function is disrupted by taxol(PMID:17276342). It has 3 isoforms produced by alternative splicing with the molecular mass of 54 kDa, 44 kDa and 50 kDa. |
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