CD55 Recombinant monoclonal antibody proteintech 82781-6-RR
$449.00
In stock
SKU
82781-6-RR
TC, DAF, CROM, CR, Complement decay-accelerating factor
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 75 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: CD55 |
| Conjugate: Unconjugated | Gene Symbol: 1604 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3086534 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: CD55, also known as DAF, is a glycosylphosphatidylinositol (GPI)-anchored surface glycoprotein that is widely distributed on blood, stroma, epithelial, and endothelial cells (PMID: 7517044; 29503741). It can also exist as a soluble form in plasma, urine, saliva, tears, and synovial fluids (PMID: 29503741). CD55 is a complement regulatory protein (PMID: 2469439; 7517044). It inhibits formation of the C3 convertases through binding to C3b and C4b. It also binds the alternate pathway convertase C3bBb, the classical pathway convertase and C4b2a to accelerate their decay (PMID: 17289551). CD55 also serves as a receptor for coxsackieviruses B1, B3, and B5 and several enteroviruses (PMID: 7538177; 7517044). The observed molecular weight of mature CD55 varies between 50 to 100 kDa depending on the cell type. Different sizes of CD55 might be caused by alternative splicing or different glycosylation patterns (PMID: 29503741). |
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