C5AR1/CD88 Recombinant monoclonal antibody proteintech 84336-6-RR
$449.00
In stock
SKU
84336-6-RR
C5AR, C5AR1, 241712G8, C5A, C5a anaphylatoxin chemotactic receptor 1
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: complement component 5a receptor 1 |
| Applications: WB, IF/ICC, ELISA | Observed Molecular Weight: 45 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: C5aR |
| Conjugate: Unconjugated | Gene Symbol: 728 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671877 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:500-1:1000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: C5aR, also named CD88, is a G protein-coupled receptor for the anaphylatoxin C5a, a cleavage product of the complement cascade. The C5a ligand is a proinflammatory component of host defense. C5aR is activated upon binding of the C5a molecule. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release, and superoxide anion production. The deduced sequence of C5aR contains 350 amino acids, giving a calculated molecular weight of 39 kDa. C5aR has an N-linked glycosylation site in the N-terminal extracellular domain. The apparent molecular weight of C5aR is about 40-52 kDa (PMID: 1847994; 9136907; 9136907; 2007135). |
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