ARID1A Recombinant monoclonal antibody proteintech 83733-3-RR
$449.00
In stock
SKU
83733-3-RR
BAF250A, BAF250, B120, AT-rich interactive domain-containing protein 1A, ARID domain-containing protein 1A
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: AT rich interactive domain 1A (SWI-like) |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 250-260 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: ARID1A |
| Conjugate: Unconjugated | Gene Symbol: 8289 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671333 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: ARID1A, also named as BAF250, BAF250A, C1orf4, OSA1 and SMARCF1, is involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). It binds DNA non-specifically. It is also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene. ARID1A belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The antibody is specific to ARID1A. |
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
