Angiopoietin 1 Recombinant monoclonal antibody proteintech 81990-4-RR
$449.00
In stock
SKU
81990-4-RR
ANGPT1, 240764D10, AGP1, AGPT, ANG 1
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse | Immunogen: angiopoietin 1 |
| Applications: WB, IHC, IF-P, FC (Intra), ELISA | Observed Molecular Weight: 70 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: Angiopoietin 1 |
| Conjugate: Unconjugated | Gene Symbol: 284 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3670511 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:1000-1:4000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: Angiopoietin 1 is a 70-kDa secreted glycoprotein generated from vascular mural cells, pericytes, and certain other cells. Angiopoietin 1 participates in vascular differentiation through angiogenesis, which is the process of the growth and remodelling of existing vessels. Angiopoietin 1 is also involved in the maintenance and turnover of blood vessels in mature animals. Angiopoietin 1 binds to and activates the TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation, playing an important role in the regulation of angiogenesis. Overexpression of Angiopoietin 1 has been proven to occur in malignant glioblastoma, neuroblastoma, non-small cell lung cancer, and other tumors. |
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