CD147 Recombinant monoclonal antibody proteintech 82909-7-RR
$449.00
In stock
SKU
82909-7-RR
EMMPRIN, Collagenase stimulatory factor, BSG, Basigin, 5F7
| Host / Isotype: Rabbit / IgG | Class: Recombinant |
| Reactivity: human | Immunogen: Fusion Protein Predict reactive species |
| Applications: WB, IF/ICC, ELISA | Observed Molecular Weight: 385 aa, 42 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC009040 |
| Conjugate: Unconjugated | Gene Symbol: CD147 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 682 |
| Application: Western Blot (WB) | RRID: AB_3670639 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: CD147, also known as Basigin or extracellular matrix metalloproteinase inducer (EMMPRIN), is a transmembrane glycoprotein that belongs to the immunoglobulin superfamily (PMID: 7812975). The molecule is composed of an intracellular portion, an extracellular portion and a single transmembrane region. CD147 is expressed on a variety of cell types (e.g., hematopoietic, epithelial, and endothelial cells) and at varying levels (PMID: 32968061). Increased expression of CD147 occurs in many tumors. CD147 is a pleiotropic molecule that plays an important role in fetal, neuronal, lymphocyte and extracellular matrix development (PMID: 17945211). CD147 has been identified as a receptor essential for erythrocyte invasion by Plasmodium falciparum (PMID: 22080952). It has been reported that spike protein of SARS-CoV-2 binds to CD147 on host cells, thereby mediating the viral invasion (Wang, Ke, et al, BioRxiv, 2020). |
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