PICK1 Recombinant monoclonal antibody proteintech 82919-1-RR
$449.00
In stock
SKU
82919-1-RR
230185B8, PICK, PRKCA binding protein, PRKCA-binding protein, PRKCABP
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat, pig | Immunogen: protein interacting with PRKCA 1 |
| Applications: WB, IHC, FC (Intra), ELISA | Observed Molecular Weight: 50 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: PICK1 |
| Conjugate: Unconjugated | Gene Symbol: 9463 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3670654 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:1000-1:8000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat, Pig | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: Protein interacting with C kinase 1 (PICK1) was first cloned as a PKC-binding partner through yeast two hybrid system. PICK1 acts as a critical regulator of membrane receptors' subcellular trafficking to modulate neural processes such as learning and memory, and is widely expressed in brain, testis, heart, lung, liver, kidney and muscle. It probably binds to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence, for instance, PICK1 is a critical mediator of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) trafficking in neural synapses. PICK1 expression on D-serine release and glutamate transport in astrocytes suggests a potential implication of PICK1 in the progression of amyotrophic lateral sclerosis (ALS). PICK1 may also participate in breast cancer development through inhibition of TGF-β signaling. |
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
