PAK7 Recombinant monoclonal antibody proteintech 82935-1-RR
$449.00
In stock
SKU
82935-1-RR
PAK4/6/7, 230201A10, EC:2.7.11.1, KIAA1264, p21-activated kinase 5
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: p21 protein (Cdc42/Rac)-activated kinase 7 |
| Applications: WB, FC (Intra), ELISA | Observed Molecular Weight: 70 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: PAK7 |
| Conjugate: Unconjugated | Gene Symbol: 57144 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3670677 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:500-1:2000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: PAK7, also known as PAK5, is a newly found but scarcely researched type II PAKs (PAK4, 5, 6). PAK7 was originally found in the brain, which promotes filopodia formation in nerve cells. Recently, studies have found that the expression level of PAK7 significantly increased in colorectal cancer, ovarian cancer, gastric cancer, neuroglioma, hepatocellular carcinoma, pancreatic cancer, osteosarcoma, and breast cancer. PAK7 plays an important role in tumorigenesis, invasion, and metastasis, mainly related to its mechanism of regulating cytoskeleton, inhibiting apoptosis, and promoting proliferation. The calculated molecular weight of PAK7 is 80 kDa (PMID: 29805709, PMID: 34165002). |