MSH3 Recombinant monoclonal antibody proteintech 82845-3-RR
$449.00
In stock
SKU
82845-3-RR
1J23, Divergent upstream protein, DUC1, DUG, hMSH3
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, rat | Immunogen: mutS homolog 3 (E. coli) |
| Applications: WB, IF/ICC, IP, ELISA | Observed Molecular Weight: 127 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: MSH3 |
| Conjugate: Unconjugated | Gene Symbol: 4437 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3086552 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Rat | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: MSH3 is a DNA mismatch repair (MMR) gene that heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. It undergoes frequent somatic mutation in colorectal cancers (CRCs) with MMR deficiency. MSH3 mismatch repair protein regulates sensitivity to cytotoxic drugs and a histone deacetylase inhibitor in human colon carcinoma cells (PMID: 23724141, PMID:32671096). |
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