ICAM-1/CD54 Recombinant monoclonal antibody proteintech 82827-8-RR
$449.00
In stock
SKU
82827-8-RR
CD54, Icam-1, MALA-2, Icam1, ICAM 1
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: mouse | Immunogen: intercellular adhesion molecule 1 |
| Applications: WB, IHC, IF-P, ELISA | Observed Molecular Weight: 85-110 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: ICAM-1 |
| Conjugate: Unconjugated | Gene Symbol: 15894 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3670567 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Mouse | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: ICAM-1 (CD54) is a transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues (PMID: 19307690). ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin (PMID: 3086451; 9694714; 15979056). It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum (PMID: 2566624; 2538244; 2475784). |
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