HLA-DMB Recombinant monoclonal antibody proteintech 82922-1-RR
$449.00
In stock
SKU
82922-1-RR
230123A3, DMB, HLA DMB, MHC class II antigen DMB, RING7
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: major histocompatibility complex, class II, DM beta |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 31 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: HLA-DMB |
| Conjugate: Unconjugated | Gene Symbol: 3109 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3670657 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). There are two classes of HLA antigens: class I (HLA-A, B and C) and class II (HLA-D). The class II molecules are composed of two non-covalently associated alpha and beta chains. HLA-DMA and HLA-DMB form a functional heterodimer that is critical in the pathway of class II antigen presentation. HLA-DM plays a critical role in catalyzing the release of Class II HLA-associated invariant chain-derived peptides (CLIP) from newly synthesized class II HLA molecules and freeing the peptide binding site for acquisition of antigenic peptides. |
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