c-MYC Recombinant monoclonal antibody proteintech 80845-1-RR
$449.00
In stock
SKU
80845-1-RR
MYC, 2B17, bHLHe39, c Myc, Class E basic helix-loop-helix protein 39
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse | Immunogen: v-myc myelocytomatosis viral oncogene homolog (avian) |
| Applications: WB, IHC, IF/ICC, FC (Intra), ELISA, ChIP-qPCR | Observed Molecular Weight: 50-65 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: MYC |
| Conjugate: Unconjugated | Gene Symbol: 4609 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_2918915 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:1000-1:4000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: MYC contains one basic helix-loop-helix (bHLH) domain. This protein is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. It seems to activate the transcription of growth-related genes. It binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. |
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