CD6 Recombinant monoclonal antibody proteintech 84166-5-RR
$449.00
In stock
SKU
84166-5-RR
241471H6
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: mouse | Immunogen: CD6 antigen |
| Applications: WB, IHC, IF-P, ELISA | Observed Molecular Weight: 130 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: Cd6 |
| Conjugate: Unconjugated | Gene Symbol: 12511 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671726 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:500-1:2000 | Conjugate: Liquid |
| Tested Reactivity: Mouse | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: CD6 is a type I transmembrane glycoprotein of 105-130 kDa that belongs to the scavenger receptor cysteine-rich superfamily (PMID: 21880988). It is composed of an extracellular region, which consists of three tandem SRCR domains, a transmembrane region, and a cytoplasmic tail devoid of intrinsic catalytic activity but harbouring several phosphorylatable residues suitable for intracellular signal transduction (PMID: 38139340; 23711376). CD6 is expressed by T cells, medullary thymocytes, a subset of B cells and NK cells, and in some cells of the brain (PMID: 1919444; 21178331). CD6 plays a role in lymphocyte activation, proliferation, and survival processes via interaction with its endogenous ligands. |
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