CD44 Recombinant monoclonal antibody proteintech 84854-5-RR
$449.00
In stock
SKU
84854-5-RR
ECMR-III, ECMR III, CSPG8, CDW44, CD44 antigen
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: CD44 molecule (Indian blood group) |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 80-95 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: CD44 |
| Conjugate: Unconjugated | Gene Symbol: 960 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): ENSG00000026508 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: CD44 is a type I transmembrane glycoprotein expressed on embryonic stem cells and in various levels on other cell types including connective tissues and bone marrow. CD44 expression is also upregulated in subpopulations of cancer cells and is recognized as a molecular marker for cancer stem cells (PMID: 29747682). It is a cell-surface receptor that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands (PMID: 10694938). Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. |
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