TAU Monoclonal antibody proteintech 66499-1-Ig
$449.00
In stock
SKU
66499-1-Ig
MAPT, 1E9A8, AT180, DDPAC, MAPTL
| Host / Isotype: Mouse / IgG2c | Class: Monoclonal |
| Reactivity: Human, Mouse, Rat, Pig And More (1) | Immunogen: CatNo: Ag21926 Product name: Recombinant human TAU protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 5-208 aa of BC000558 Sequence: PRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENL Predict reactive species |
| Applications: WB, IHC, IF, ELISA | Observed Molecular Weight: 37-46, 79-81 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC000558 |
| Conjugate: Unconjugated | Gene Symbol: TAU |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 4137 |
| Application: Western Blot (WB) | RRID: AB_2881863 |
| Dilution: WB : 1:1000-1:30000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat, Pig | Form: Liquid |
| Host / Isotype: Mouse / IgG2c | Background Information: The microtubule-associated protein TAU (MAPT or TAU) is encoded by MAPT gene, which locates on human chromosome 17q21, binds to the tubulin subunit of microtubule and promotes its assembly and stability. Most TAU is expressed in neurons, and TAU isoform is expressed in the peripheral nervous system while the others are expressed in the central nervous system. TAU links axonal microtubules with C-terminus to neural plasma membrane components with its N-terminus, suggesting the participation in intracellular signal transduction and neuron's development and viability. Various isoforms of Tau exist due to the alternative splicing, and short isoforms around 45-69 kDa and long isoforms around 100-110 kDa have been reported in different literature (PMID:8752131,15965697, 12485403).Present monoclonal anti-Tau antibody can detect approx 100-kDa bands in brain tissues. |
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