Caspase 12 Polyclonal antibody proteintech 55238-1-AP

$449.00
In stock
SKU
55238-1-AP

 

CASP 12, CASP12, CASP12P1, Caspase 12, caspase 12 (gene/pseudogene), Caspase12, Inactive caspase 12

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human And More (2) Immunogen: Peptide Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, ELISA Observed Molecular Weight: 39 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: NR_000035
Conjugate: Unconjugated Gene Symbol: Caspase 12
Tested Applications: Positive WB detected in Gene ID (NCBI): 120329
Application: Western Blot (WB) RRID: AB_10892670
Dilution: WB : 1:500-1:2000 Conjugate: Unconjugated
Tested Reactivity: Human Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: Caspase 12 is an enzyme known as a cysteine protease. It belongs to a family of enzymes called caspases that cleave their substrates at C-terminal aspartic acid residues. It is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. Caspase-12 is located in the endoplasmic reticulum (ER). It is responsible for ER-stress-induced apoptosis, such as high calcium concentration, low oxygen and low glucose levels. Caspase-12 Antibody detects endogenous levels of full-length caspase-12 protein (50 kDa) and its cleaved product (40-44 kDa). This antibody does not cross-react with other caspases.

 

 

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