TLR3/CD283 Recombinant monoclonal antibody proteintech 83136-3-RR
$449.00
In stock
SKU
83136-3-RR
TLR3, 230445G4, CD283, toll like receptor 3, Toll-like receptor 3
| Host / Isotype: Rabbit / IgG | Class: Recombinant |
| Reactivity: human | Immunogen: CatNo: Ag34044 Product name: Recombinant human TLR3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 725-904 aa of BC094737 Sequence: FEGWRISFYWNVSVHRVLGFKEIDRQTEQFEYAAYIIHAYKDKDWVWEHFSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSIKRSRKIIFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIPDYKLNHALCLRRGMFKSHCILNWPVQKERIGAFRHKLQVALGSKNSVH Predict reactive species |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 904 aa, 104 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC094737 |
| Conjugate: Unconjugated | Gene Symbol: TLR3 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 7098 |
| Application: Western Blot (WB) | RRID: AB_3670837 |
| Dilution: WB : 1:2000-1:14000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: TLR3 belongs to the Toll-like receptor family which is important in the innate immune response to pathogens. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. TLR3 is a nucleotide-sensing TLR that is activated by double-stranded RNA. Upon recognition of dsRNA, TLR3 transmits signals via the adaptor protein TICAM-1/TRIF, leading to the induction of type I IFN, cytokine/chemokine production, and dendritic cell (DC) maturation (PMID: 18262679). Western detected full-length (?120 kD) and cleaved (?70 kDa) TLR3 (PMID: 28717003). |
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
