ACTN4 Monoclonal antibody proteintech 66628-1-Ig
$449.00
In stock
SKU
66628-1-Ig
Alpha actinin 4, 1E12B8, ACTININ 4, Actinin alpha 4, actinin, alpha 4
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: human, mouse, rat | Immunogen: CatNo: Ag13549 Product name: Recombinant human ACTN4 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 612-911 aa of BC005033 Sequence: TTVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQFASQANVVGPWIQTKMEEIGRISIEMNGTLEDQLSHLKQYERSIVDYKPNLDLLEQQHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMQEFRASFNHFDKDHGGALGPEEFKACLISLGYDVENDRQGEAEFNRIMSLVDPNHSGLVTFQAFIDFMSRETTDTDTADQVIASFKVLAGDKNFITAEELRRELPPDQAEYCIARMAPYQGPDAVPGALDYKSFSTALYGESDL Predict reactive species |
| Applications: WB, IHC, IF, IP, ELISA | Observed Molecular Weight: 105 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC005033 |
| Conjugate: Unconjugated | Gene Symbol: ACTN4 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 81 |
| Application: Western Blot (WB) | RRID: AB_2881988 |
| Dilution: WB : 1:5000-1:20000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat | Form: Liquid |
| Host / Isotype: Mouse / IgG1 | Background Information: ACTN4 (alpha actinin 4) is a ubiquitous actin-binding protein that cross-links actin filaments into bundles to form filopodia, and has a crucial role in cytoskeletal organization. ACTN4 is colocalized with actin stress fibers and is dispersed in the cytoplasm and in the nucleus. Increased levels of ACTN4 have been associated with cancer metastasis, indicating its implication in cancer cell migration and metastasis. Defects in ACTN4 cause glomerular disease. This antibody recognizes 105 and 80 kDa of endogenous ACTN4 protein in various lysates. (22370640, 10700177) |
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