TMEM173/STING Recombinant monoclonal antibody proteintech 80165-1-RR
$449.00
In stock
SKU
80165-1-RR
STING, 7K7, Endoplasmic reticulum interferon stimulator, ERIS, MITA
| Host / Isotype: Rabbit / IgG | Class: Recombinant |
| Reactivity: Human And More (1) | Immunogen: CatNo: Ag13921 Product name: Recombinant human TMEM173 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 174-379 aa of BC047779 Sequence: ELQARIRTYNQHYNNLLRGAVSQRLYILLPLDCGVPDNLSMADPNIRFLDKLPQQTGDHAGIKDRVYSNSIYELLENGQRAGTCVLEYATPLQTLFAMSQYSQAGFSREDRLEQAKLFCRTLEDILADAPESQNNCRLIAYQEPADDSSFSLSQEVLRHLRQEEKEEVTVGSLKTSAVPSTSTMSQEPELLISGMEKPLPLRTDFS Predict reactive species |
| Applications: WB, IHC, IF/ICC, IF-P, IF-Fro, IP, ELISA | Observed Molecular Weight: 379 aa, 42 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC047779 |
| Conjugate: Unconjugated | Gene Symbol: STING |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 340061 |
| Application: Western Blot (WB) | RRID: AB_2918870 |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: Stimulator of interferon genes (STING, also known as ERIS, MITA and MPYS, and encoded by TMEM173) is a transmembrane adaptor protein that facilitates innate immune signaling (PMID: 18724357). STING is widely expressed in various cell types such as endothelial cells, epithelial cells, T cells, macrophages, and dendritic cells (PMID: 26603901). It is predominantly located in the endoplasmic reticulum (ER). STING functions as a sensor of cytosolic DNA and promotes the production of type I interferons and pro-inflammatory cytokines. |