GNRHR Polyclonal antibody proteintech 19950-1-AP
$449.00
In stock
SKU
19950-1-AP
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human, Mouse And More (3) | Immunogen: Peptide Predict reactive species |
| Applications: WB, IHC, IF, FC (Intra), ELISA | Observed Molecular Weight: 38 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_000406 |
| Conjugate: Unconjugated | Gene Symbol: GNRHR |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 2798 |
| Application: Western Blot (WB) | RRID: AB_10644155 |
| Dilution: WB : 1:1000-1:6000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: GNRHR, also named GRHR, belongs to the G-protein coupled receptor 1 family. GNRHR is a receptor for GnRH that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform2 of GNRHR may act as an inhibitor of GnRH-R signaling. Defects in GNRHR are a cause of idiopathic hypogonadotropic hypogonadism (IHH). Defects in GNRHR are a cause of fertile eunuch syndrome. The antibody only recognizes the isoform1 of GNRHR. The predicted unmodified molecular weight of the human GNRHR is ~38 kDa, the larger band (50-65 kDa) is likely to represent a glycosylated form of GNRHR. |
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