Anti-Human CD11b (ICRF44) proteintech 65116-1-Ig
$93.00
In stock
SKU
65116-1-Ig
| Host / Isotype: Mouse / IgG1, kappa | Class: Monoclonal |
| Reactivity: Human And More (1) | Immunogen: Rheumatoid synovial cells and human monocytes Predict reactive species |
| Applications: FC | Observed Molecular Weight: 1152 aa, 127 kDa |
| Formulation: PBS, Azide | GenBank Accession Number: CD11b |
| Conjugate: Unconjugated | Gene Symbol: 3684 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): ENSG00000169896 |
| Application: Flow Cytometry (FC) | RRID: AB_2918412 |
| Dilution: FC : 0.5 ug per 10^6 cells in 100 μl suspension | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Mouse / IgG1, kappa | Background Information: Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828). |
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