CD206 Recombinant monoclonal antibody proteintech 81525-1-RR
$449.00
In stock
SKU
81525-1-RR
1G15, CLEC13D, CLEC13DL, C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like
| Host / Isotype: Rabbit / IgG | Class: Recombinant |
| Reactivity: human, rat, pig | Immunogen: Peptide Predict reactive species |
| Applications: WB, IHC, IF-P, ELISA | Observed Molecular Weight: 166 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_002438 |
| Conjugate: Unconjugated | Gene Symbol: CD206 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 4360 |
| Application: Western Blot (WB) | RRID: AB_2935558 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Rat, Pig | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane protein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains (responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail. It is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia. |
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