Caspase 3/P17/P19 Recombinant monoclonal antibody proteintech 82202-1-RR
$449.00
In stock
SKU
82202-1-RR
CASP3, Caspase3, 5G20, CASP 3, CASP-3
| Host / Isotype: Rabbit / IgG | Class: Recombinant |
| Reactivity: Human, Mouse And More (3) | Immunogen: Peptide Predict reactive species |
| Applications: WB, IHC, IF/ICC, FC (Intra), ELISA | Observed Molecular Weight: 32 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_004346 |
| Conjugate: Unconjugated | Gene Symbol: Caspase 3 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 836 |
| Application: Western Blot (WB) | RRID: AB_3086469 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: Caspases, a family of endoproteases, are critical players in cell regulatory networks controlling inflammation and cell death. Initiator caspases (caspase-2, -8, -9, -10, -11, and -12) cleave and activate downstream effector caspases (caspase-3, -6, and -7), which in turn execute apoptosis by cleaving targeted cellular proteins. Caspase 3 (also named CPP32, SCA-1, and Apopain) proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at the beginning of apoptosis. Caspase 3 plays a key role in the activation of sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Caspase 3 can also form heterocomplex with other proteins and performs the molecular mass of 50-70 kDa. This antibody can recognize p17, p19 and p32 of Caspase 3. |
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