Hsc70 Monoclonal antibody proteintech 66442-1-Ig

$449.00
In stock
SKU
66442-1-Ig

 

HSPA8, 1A4B3, EC:3.6.4.10, Heat shock cognate 71 kDa protein, Heat shock protein family A member 8

Host / Isotype: Mouse / IgG1 Class: Monoclonal
Reactivity: Human, Mouse, Rat And More (3) Immunogen: CatNo: Ag17910 Product name: Recombinant human Hsc70 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 288-587 aa of BC007276 Sequence: QKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD Predict reactive species
 Applications: WB, IHC, IF/ICC, ELISA Observed Molecular Weight: 70 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC007276
Conjugate: Unconjugated Gene Symbol: HSC70
Tested Applications: Positive WB detected in Gene ID (NCBI): 3312
Application: Western Blot (WB) RRID: AB_2881812
Dilution: WB : 1:20000-1:100000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Mouse / IgG1 Background Information: HSPA8 (also known as HSC70) is a member of the HSPA (HSP70) family of heat-shock proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. HSPA8 is a constitutively expressed cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Recently it has been reported that HSPA8 can interact with α-synuclein, the critical pathological protein of Parkinson's disease, indicating its implication in neurodegenerative disease. (PMID: 21832061)

 

 

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