Phospho-IkB Alpha (Ser32/36) Recombinant monoclonal antibody proteintech 82349-1-RR
$449.00
In stock
SKU
82349-1-RR
IκBα (Ser 32/36), p IkB Alpha, p IkB Alpha (Ser32/36), p IkB Alpha Ser32/36, p IkB α
| Host / Isotype: Rabbit / IgG | Class: Recombinant |
| Reactivity: Human, Mouse, Rat And More (3) | Immunogen: Peptide Predict reactive species |
| Applications: WB, IHC, IF, FC (Intra), ELISA | Observed Molecular Weight: 36 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC004983 |
| Conjugate: Unconjugated | Gene Symbol: IkB Alpha |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 4792 |
| Application: Western Blot (WB) | RRID: AB_3073626 |
| Dilution: WB : 1:1000-1:4000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (NFKBIA, synonyms: IKBA, MAD-3, NFKBI). NFKB1 or NFKB2 is bound to REL, RELA , or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime. The antibody also detects the phosphorylated form of the NFKBIA (IkB Alpha) (PMID:?16904979, PMID:?28990531 PMID:?10455908). |
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
