Phospho-SMAD1 (Ser214) Recombinant monoclonal antibody proteintech 81433-1-RR
$449.00
In stock
SKU
81433-1-RR
p SMAD1, p SMAD1 (Ser214), p SMAD1 Ser214, Phospho SMAD1, Phospho SMAD1 (Ser214)
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse | Immunogen: SMAD family member 1 |
| Applications: WB, ELISA | Observed Molecular Weight: 52 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: SMAD1 |
| Conjugate: Unconjugated | Gene Symbol: 4086 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_2923717 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:16800 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: SMAD family member 1 (Smad1) have been involved in metastatic progression of many cancer types. Smad1 can be induced by many tumor-stimulating cytokines such as the bone morphogenetic protein 2 (BMP2) and TNFα and plays important roles in cell invasion and metastasis. BMP2 signalling is initiated by binding to its specific receptors, which leads to in the phosphorylation and nuclear translocation of Smad1. Translocated Smad1 then modulates the expression of downstream osteogenic genes. (PMID:?32954678, PMID:?30008908) |
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