IL-27A p28 Monoclonal antibody proteintech 66164-1-Ig
$449.00
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66164-1-Ig
| Host / Isotype: Mouse / IgG2b | Class: Monoclonal |
| Reactivity: human | Immunogen: CatNo: Ag21436 Product name: Recombinant human IL-27 protein Source: e coli.-derived, PET30a Tag: 6*His Domain: 19-243 aa of BC062422 Sequence: LLLVQAGVWGFPRPPGRPQLSLQELRREFTVSLHLARKLLAEVRGQAHRFAESHLPGVNLYLLPLGEQLPDVSLTFQAWRRLSDPERLCFISTTLQPFHALLGGLGTQGRWTNMERMQLWAMRLDLRDLQRHLRFQVLAAGFNLPEEEEEEEEEEEEERKGLLPGALGSALQGPAQVSWPQLLSTYRLLHSLELVLSRAVRELLLLSKAGHSVWPLGFPTLSPQP Predict reactive species |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 243 aa, 27 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC062422 |
| Conjugate: Unconjugated | Gene Symbol: IL-27 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 246778 |
| Application: Western Blot (WB) | RRID: AB_2881560 |
| Dilution: WB : 1:2000-1:20000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Mouse / IgG2b | Background Information: IL-27, as a member of the IL-6/IL-12 family, is a heterodimeric cytokine composed of two subunits: p28 (IL-27a) and EBI3 (IL-27b). IL-27 acts on various cell types, including T cells, B cells, macrophages, dendritic cells, natural killer (NK) cells and non-hematopoietic cells. IL-27 plays a critical role in the early regulation of T helper type 1 initiation, and enhances proliferation of naive CD4+T cells and naive B cells. It, however, also exerts anti-inflammatory functions by inhibiting the development of Th17 cells and inducing IL-10 producing type 1 regulatory T cells. IL-27 is a potentially promising cytokine for therapeutic approaches on various human diseases. |
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