Histone H2B Monoclonal antibody proteintech 68393-1-Ig
$449.00
In stock
SKU
68393-1-Ig
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: human, mouse, rat, chicken, zebrafish | Immunogen: Peptide Predict reactive species |
| Applications: WB, IHC, IF/ICC, FC (Intra), ELISA | Observed Molecular Weight: 14 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC005827 |
| Conjugate: Unconjugated | Gene Symbol: Histone H2B |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 8349 |
| Application: Western Blot (WB) | RRID: AB_3085110 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat, Chicken, Zebrafish | Form: Liquid |
| Host / Isotype: Mouse / IgG1 | Background Information: Histones are nuclear proteins that are classified into five major protein groups: histones H2A, H2B, H3, and H4 are known as the core histones. Post-translationally modified H2B proteins can modulate the nucleosome/chromatin structure or DNA accessibility to affect the transcriptional pathways linked to embryonic development and cell differentiation. Monoubiquitination of histone H2B has emerged as an important chromatin modification with roles not only in transcription but also in cell differentiation, DNA repair or mRNA processing(PMID: 25027370). |