GPI Monoclonal antibody proteintech 67178-1-Ig
$449.00
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SKU
67178-1-Ig
| Host / Isotype: Mouse / IgG1 | Class: Antibody |
| Reactivity: human | Immunogen: glucose phosphate isomerase |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 55-64 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: GPI |
| Conjugate: Unconjugated | Gene Symbol: 2821 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_2882474 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein G purification |
| Host / Isotype: Monoclonal | Background Information: GPI(Glucose-6-phosphate isomerase), which is also named as autocrine motility factor (AMF), phosphoglucose isomerase(PGI), Neuroleukinis(NLK), phosphohexose isomerase(PHI) or sperm antigen 36(SA-36), is a housekeeping cytosolic enzyme that plays a key role in both glycolysis and gluconeogenesis pathways. It is also a multifunctional protein that displays cytokine properties, eliciting mitogenic, motogenic, and differentiation activities, and has been implicated in tumor progression and metastasis (PMID:12783864, 19603112). This protein can exsit as a homodimer in the catalytically active form and a monomer in the secreted form (PMID:11371164). It has 2 isoforms produced by alternative splicing with the calculated molecular mass of 63-64kDa, and an apparent molecular mass of 55 and 64 kDa under non-reducing and reducing conditions, respectively(PMID: 19603112, 11004567). |
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