GDI2 Monoclonal antibody proteintech 60078-1-Ig

$449.00
In stock
SKU
60078-1-Ig

 

Host / Isotype: Mouse / IgG1 Class: Monoclonal
Reactivity: human, mouse, rat Immunogen: CatNo: Ag4613 Product name: Recombinant human GDI2 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-234 aa of BC005145 Sequence: MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALALYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGEL Predict reactive species
 Applications: WB, IHC, IF/ICC, ELISA Observed Molecular Weight: 47 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC005145
Conjugate: Unconjugated Gene Symbol: GDI2
Tested Applications: Positive WB detected in Gene ID (NCBI): 2665
Application: Western Blot (WB) RRID: AB_2232457
Dilution: WB : 1:2000-1:10000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Mouse / IgG1 Background Information: GDP dissociation inhibitors (GDIs) are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, GDIs can bind and release GDP-bound Rab proteins from membranes. Two GDI proteins towards different Rab proteins have been identified. GDI1 interacts with almost all of the Rab proteins, while GDI2 interacts with Rabll but not Rab3A. GDI2 distributes ubiquitously, displaying a membrane bound location in perinuclear regions of cells. GDI-2 was thought to be involved in cellular response to insulin. It electrophoreses as a 46kd protein in SDS-PAGE. (PMID: 7929030; PMID: 19570034). This antibody can bind both GDIs for the close sequences.

 

 

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