FURIN Monoclonal antibody proteintech 67481-1-Ig
$449.00
In stock
SKU
67481-1-Ig
| Host / Isotype: Mouse / IgG1 | Class: Antibody |
| Reactivity: Human, Mouse | Immunogen: furin (paired basic amino acid cleaving enzyme) |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 90-110 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: FURIN |
| Conjugate: Unconjugated | Gene Symbol: 5045 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_2882708 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:1000-1:5000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse | Form: Protein G purification |
| Host / Isotype: Monoclonal | Background Information: FURIN, also named as FUR, PACE, PCSK3, SPC1, Kex2p, is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif. Furin is synthesized as an inactive zymogen that may minimize the occurrence of premature enzymatic activity that would lead to alternative protein activation or degradation. Glycosylation and other post-translational modifications can make the pre-pro furin run at 100-110 kDa, the mature furin at 98-95 kDa and shed furin at 90 kDa. |
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