BSAP,PAX5 Monoclonal antibody proteintech 60349-1-Ig
$449.00
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60349-1-Ig
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: human | Immunogen: CatNo: Ag16023 Product name: Recombinant human BSAP,PAX5 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 145-391 aa of BC156927 Sequence: QPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYPIVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRFPNPGLLGSPYYYSAAARGAAPPAAATAYDRH Predict reactive species |
| Applications: WB, IHC, IF, FC (Intra), IP, ELISA | Observed Molecular Weight: 391 aa, 42 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC156927 |
| Conjugate: Unconjugated | Gene Symbol: PAX5 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 5079 |
| Application: Western Blot (WB) | RRID: AB_2881458 |
| Dilution: WB : 1:500-1:3000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Mouse / IgG1 | Background Information: PAX5, also named B-cell specific activator protein (BSAP), is a member of the highly conserved paired box (PAX)-domain family of transcription factors. PAX5 is essential in normal B-cell lymphopoiesis. It is expressed in pro-B, pre-B and mature B lymphocytes but not in plasma cells. PAX5 is a common target in leukemogenesis of B-ALL ( B-lineage acute lymphoblastic leukemia) along with CDKN2A. Owing to its frequent deletion in B-ALL, PAX5 could be used as one of the molecular markers in diagnosis and monitoring of the disease. This antibody is specific to PAX5. It will not cross react with other PAX members. |
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