Anti-Rat CD86 (24F) proteintech 65224-1-Ig
$441.00
In stock
SKU
65224-1-Ig
| Host / Isotype: Mouse / IgG1, kappa | Class: Monoclonal |
| Reactivity: rat | Immunogen: HTLV-1-transformed Lewis-S1 rat T cell line Predict reactive species |
| Applications: IF, FC | Observed Molecular Weight: 36 kDa |
| Formulation: PBS, Azide | GenBank Accession Number: Cd86 |
| Conjugate: Unconjugated | Gene Symbol: 56822 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): AB_3670278 |
| Application: Flow Cytometry (FC) | RRID: Unconjugated |
| Dilution: FC : 0.5 ug per 10^6 cells in 100 μl suspension | Conjugate: Liquid |
| Tested Reactivity: Rat | Form: Affinity purification |
| Host / Isotype: Mouse / IgG1, kappa | Background Information: CD86 (also known as B7.2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. |
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