FXR1 Polyclonal antibody proteintech 13194-1-AP

$449.00
In stock
SKU
13194-1-AP

 

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human, Mouse And More (2) Immunogen: CatNo: Ag3873 Product name: Recombinant human FXR1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-353 aa of BC028983 Sequence: MAELTVEVRGSNGAFYKGFIKDVHEDSLTVVFENNWQPERQVPFNEVRLPPPPDIKKEISEGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYVIEYAACDATYNEIVTFERLRPVNQNKTVKKNTFFKCTVDVPEDLREACANENAHKDFKKAVGACRIFYHPETTQLMILSASEATVKRVNILSDMHLRSIRTKLMLMSRNEEATKHLECTKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQARKVPGVTAIELDEDTGTFRIYGESADAVKKARGFLEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKLPREDGMVPFVFVGTKESIGNVQVLLEY Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, RIP, ELISA Observed Molecular Weight: 621 aa, 70 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC028983
Conjugate: Unconjugated Gene Symbol: FXR1
Tested Applications: Positive WB detected in Gene ID (NCBI): 8087
Application: Western Blot (WB) RRID: AB_2110702
Dilution: WB : 1:5000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: Tumour necrosis factor-alpha (TNF-alpha) is a key mediator of inflammation in host defence against infection and in autoimmune disease. Its production is controlled post-transcriptionally by multiple RNA-binding proteins that interact with the TNF-alpha AU-rich element and regulate its expression; Fragile X mental retardation-related protein 1 (FXR1) is one of these. FXR1 (fragile-X-mental retardation-related protein 1) are RNA-binding proteins that have been demonstrated to impact miRNA-mediated, post-transcriptional gene regulation, and required for embryonic and postnatal development of muscle tissue. It can regulate intracellular transport and local translation of certain mRNAs. The FXR1 exists some isoforms with the MW 69 kDa and 60 kDa.

 

 

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