SPTLC1 Monoclonal antibody proteintech 66899-1-Ig

$449.00
In stock
SKU
66899-1-Ig

 

Host / Isotype: Mouse / IgG1 Class: Monoclonal
Reactivity: human, mouse, rat Immunogen: CatNo: Ag7876 Product name: Recombinant human SPTLC1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-143 aa of BC007085 Sequence: MATATEQWVLVEMVQALYEAPAYHLILEGILILWIIRLLFSKTYKLQERSDLTVKEKEELIEEWQPEPLVPPVPKDHPALNYNIVSGPPSHKTVVNGKECINFASFNFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFE Predict reactive species
 Applications: WB, IHC, IF/ICC, ELISA Observed Molecular Weight: 53 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC007085
Conjugate: Unconjugated Gene Symbol: SPTLC1
Tested Applications: Positive WB detected in Gene ID (NCBI): 10558
Application: Western Blot (WB) RRID: AB_2882228
Dilution: WB : 1:5000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Mouse / IgG1 Background Information: SPTLC1 is a subunit of serine palmitoyltransferase (SPT) which is the key enzyme in sphingolipid biosynthesis and is essential for embryogenesis and cell survival. Mutations in the SPTLC1 gene (C133W, C133Y, V144D, and G387A) were reported to be responsible for the development of an inherited sensory neuropathy (hereditary sensory neuropathy type I, HSN1).

 

 

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