MTMR14 Monoclonal antibody proteintech 67561-1-Ig

$449.00
In stock
SKU
67561-1-Ig

 

C3orf29, FLJ22405, FLJ46453, FLJ90311, hEDTP, HJUMPY, MTMR14, NS5ATP4ABP1

Host / Isotype: Mouse / IgG2b Class: Monoclonal
Reactivity: Human, Mouse, Rat And More (1) Immunogen: CatNo: Ag6883 Product name: Recombinant human MTMR14 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 245-598 aa of BC050626 Sequence: LSIPYPGCEFFKEYKDRDYMAEGLIFNWKQDYVDAPLSIPDFLTHSLNIDWSQYQCWDLVQQTQNYLKLLLSLVNSDDDSGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVDRLSKGEEIFFFCFNFLKHITSEEFSALKTQRRKSLPARDGGFTLEDICMLRRKDRGSTTSLGSDFSLVMESSPGATGSFTYEAVELVPAGAPTQAAWRKSHSSSPQSVLWNRPQPSEDRLPSQQGLAEARSSSSSSSNHSDNFFRMGSSPLEVPKPRLAALSDRETRLQEVRSAFLAAYSSTVGLRAVAPSPSGAIGGLLEQFARGVGLRSISSNAL Predict reactive species
 Applications: WB, IHC, IF-P, ELISA Observed Molecular Weight: 72 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC050626
Conjugate: Unconjugated Gene Symbol: MTMR14
Tested Applications: Positive WB detected in Gene ID (NCBI): 64419
Application: Western Blot (WB) RRID: AB_2882775
Dilution: WB : 1:1000-1:6000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Mouse / IgG2b Background Information: MTMR14, also known as Jumpy, belongs to the MTM1/MTMRs family which has 15 members that divided into two subgroup: catalytically inactive and active. MTMR14 is a catalytically active member possessing an active phosphatase domain, that specifically dephosphorylates PI3P and phosphatidylinositol (3,5)-bisphosphate (PI3,5P2) at position 3 on inositol ring. A remarkable feature of the MTM1/MTMRs family is the association between a catalytically inactive member and a catalytically active member, which plays an important regulatory role. MTMR14 has 3 isoforms with molecular weight of 60-72 kDa, and also can be detected as a higher molecular weight due to the heterodimerization with other MTMR members.

 

 

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