XDH Polyclonal antibody proteintech 55156-1-AP
$449.00
In stock
SKU
55156-1-AP
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human, Mouse, Rat And More (3) | Immunogen: Peptide Predict reactive species |
| Applications: WB, IHC, IF, ELISA | Observed Molecular Weight: 146 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_000379 |
| Conjugate: Unconjugated | Gene Symbol: XDH |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 7498 |
| Application: Western Blot (WB) | RRID: AB_10860905 |
| Dilution: WB : 1:500-1:2000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: XDH, also named as XDHA, XO and XD, belongs to the xanthine dehydrogenase family. It catalyzes the last two steps of purine catabolism in man, formation of the end product uric acid from hypoxanthine and xanthine. The mammalian enzyme is synthesized as a dehydrogenase (XDH), which uses NAD as the electron acceptor, but it can be converted into an oxidase (XO) both in vivo and in vitro.This gene encodes a protein of 150 kDa and the 150 kDa polypeptide can be processed into a fragment of 130 kDa and further to 85 kDa by spontaneous proteolytic cleavage(PMID:9989587). In addition, the full length polypeptide can be also partially processed into a 87 kDa and 59 kDa fragments(PMID:21528298). It also can exsit as a homodimer(PMID:9989587). This antibody is specific to XDH. |
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