Factor XII Monoclonal antibody proteintech 66089-1-Ig
$449.00
In stock
SKU
66089-1-Ig
F12, Factor 12, EC:3.4.21.38, Coagulation factor XII, Beta-factor XIIa part 1
| Host / Isotype: Mouse / IgG2b | Class: Monoclonal |
| Reactivity: human, mouse | Immunogen: CatNo: Ag3401 Product name: Recombinant human F12 protein Source: e coli.-derived, T-HIS Tag: 6*His Domain: 316-615 aa of BC012390 Sequence: MPAQPAPPKPQPTTRTPPQSQTPGALPAKREQPPSLTRNGPLSCGQRLRKSLSSMTRVVGGLVALRGAHPYIAALYWGHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVCLPSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYLAWIREHTVS Predict reactive species |
| Applications: WB, IHC, IF/ICC, IF-P, ELISA | Observed Molecular Weight: 615 aa, 68 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC012390 |
| Conjugate: Unconjugated | Gene Symbol: Factor XII |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 2161 |
| Application: Western Blot (WB) | RRID: AB_11232031 |
| Dilution: WB : 1:500-1:2000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse | Form: Liquid |
| Host / Isotype: Mouse / IgG2b | Background Information: Factor XII (F XII, Hageman factor) is a 80 kDa, single chain glycoprotein that circulates in blood as an inactive zymogen. F XII plays an important role in blood coagulation, fibrinolysis, and kinin generation. Factor XII is activated by kallikrein in alpha-factor XIIa, which is further converted by trypsin into beta-factor XIIa. Alpha-factor XIIa is composed of a 52 kDa NH2-terminal heavy chain, called coagulation factor XIIa heavy chain, and a 28 kDa COOH-terminal light chain, called coagulation factor XIIa light chain, connected by a disulfide bond. Beta-factor XIIa is composed of 2 chains linked by a disulfide bond, an N-terminal nonapeptide, called beta-factor XIIa part 1, and coagulation factor XIIa light chain, also known in this context as beta-factor XIIa part 2. |
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
