ERAP2 Monoclonal antibody proteintech 67477-1-Ig

$449.00
In stock
SKU
67477-1-Ig

 

ERAP2, FLJ23633, FLJ23701, FLJ23807, L RAP, LRAP

Host / Isotype: Mouse / IgG2b Class: Monoclonal
Reactivity: Human, Rat And More (1) Immunogen: CatNo: Ag30061 Product name: Recombinant human ERAP2 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 41-180 aa of BC065240 Sequence: PSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFY Predict reactive species
 Applications: WB, ELISA Observed Molecular Weight: 110 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC065240
Conjugate: Unconjugated Gene Symbol: ERAP2
Tested Applications: Positive WB detected in Gene ID (NCBI): 64167
Application: Western Blot (WB) RRID: AB_2882704
Dilution: WB : 1:1000-1:5000 Conjugate: Unconjugated
Tested Reactivity: Human, Rat Form: Liquid
Host / Isotype: Mouse / IgG2b Background Information: ERAP2(Endoplasmic reticulum aminopeptidase 2) is also named as LRAP(Leukocyte-derived arginine aminopeptidase). It plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. ERAP2 can form heterodimers with ERAP1(PMID:15908954). Defects in the expression of ERAP2 may cause improper antigen processing, possibly leading to favor tumor escape from the immune surveillance. ERAP2 has the calculated molecular mass of 105-110 kDa, and apparent molecular mass of 120 kDa duo to the glycosylation.

 

 

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