APOB Polyclonal antibody proteintech 20578-1-AP
$449.00
In stock
SKU
20578-1-AP
Apolipoprotein B, Apo B, Apo B-100, ApoB100, ApoB48
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human, Mouse And More (2) | Immunogen: Peptide Predict reactive species |
| Applications: WB, IHC, IF-P, ELISA | Observed Molecular Weight: 516 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_000384 |
| Conjugate: Unconjugated | Gene Symbol: APOB |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 338 |
| Application: Western Blot (WB) | RRID: AB_10732938 |
| Dilution: WB : 1:1000-1:8000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: The apolipoprotein B (APOB) is a plasma protein synthesized primarily in the liver and intestine and play an important role in lipid and cholesterol metabolism. The APOB encodes two different isoproteins through mRNA editing, APOB-48 and APOB-100. APOB-48 and APOB-100 is present in both human liver and intestine. APOB-100 is essential for the assembly of VLDL in the liver. APOB-48 is essential for the assembly of chylomicrons in the intestine. It is well established that APOB-100 levels are associated with coronary heart disease. Unlike humans and rabbits, rats and mice secrete both apoB-100- and apoB-48-containing lipoproteins from the liver as a result of the hepatic expression of APOBEC-1 (PMID: 9633945). This antibody recognizes both of APOB-48, APOB-100 (PMID:11839763, PMID:2450346). |
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