RUNX2 Polyclonal antibody proteintech 20700-1-AP
$449.00
In stock
SKU
20700-1-AP
AML3, AML-3, CBF-alpha-1, Core-binding factor subunit alpha-1, OSF 2
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human, Rat And More (4) | Immunogen: Peptide Predict reactive species |
| Applications: WB, IHC, IF/ICC, FC (Intra), IP, chIP, ELISA | Observed Molecular Weight: 57 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_004348 |
| Conjugate: Unconjugated | Gene Symbol: RUNX2 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 860 |
| Application: Western Blot (WB) | RRID: AB_2722783 |
| Dilution: WB : 1:200-1:1000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Rat | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: RUNX2, also named as AML3, CBFA1, OSF2 and PEBP2A, is a Transcription factor which involved in osteoblastic differentiation and skeletal morphogenesis. It is essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters By similarity. RUNX2 inhibits MYST4-dependent transcriptional activation. The antibody is specific to RUNX2. |
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