Calpastatin Monoclonal antibody proteintech 67107-1-Ig
$449.00
In stock
SKU
67107-1-Ig
CAST, 1G12A2, Calpain inhibitor, Sperm BS-17 component
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: Human And More (1) | Immunogen: CatNo: Ag28669 Product name: Recombinant human CAST protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-350 aa of BC013579 Sequence: MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEK Predict reactive species |
| Applications: WB, IF/ICC, FC (Intra), ELISA | Observed Molecular Weight: 667 aa, 72 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC013579 |
| Conjugate: Unconjugated | Gene Symbol: Calpastatin |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 831 |
| Application: Western Blot (WB) | RRID: AB_2882411 |
| Dilution: WB : 1:1000-1:6000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Mouse / IgG1 | Background Information: Calpastatin (CAST) is an endogenous protein that specifically inhibits the activity of calpains, a family of calcium-dependent proteases involved in numerous cellular processes. The CAST gene encodes calpastatin, which contains multiple calpain-inhibiting domains that bind to the active site of calpain, preventing it from performing its functions. Calpastatin is found in the cytosol and plays a key role in regulating intracellular proteolysis, with malfunctions in the calpain-calpastatin system linked to various diseases, including autoimmune disorders and neurodegenerative conditions |
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