Napsin A Monoclonal antibody proteintech 60259-2-Ig

$449.00
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60259-2-Ig

 

NAPSA, 1H7F2, Asp 4, ASP4, Aspartyl protease 4

Host / Isotype: Mouse / IgG1 Class: Monoclonal
Reactivity: human Immunogen: CatNo: Ag9721 Product name: Recombinant human NAPSA protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-420 aa of BC017842 Sequence: MSPPPLLQPLLLLLPLLNVEPSGATLIRIPLHRVQPGRRTLNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAFAHFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPAHYIPPLTFVPVTVPAYWQIHMERVKVGPGLTLCAKGCAAILDTGTSLITGPTEEIRALHAAIGGIPLLAGEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQALDVPPPAGPFWILGDVFLGTYVAVFDRGDMKSSARVGLARARTRGADLGWGETAQAQFPG Predict reactive species
 Applications: IHC, IF/ICC, FC (Intra), ELISA Observed Molecular Weight: 420 aa, 45 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: Napsin A
Conjugate: Unconjugated Gene Symbol: 9476
Tested Applications: Positive IHC detected in Gene ID (NCBI): AB_2881381
Application: Immunohistochemistry (IHC) RRID: Unconjugated
Dilution: IHC : 1:10000-1:60000 Conjugate: Liquid
Tested Reactivity: Human Form: Protein G purification
Host / Isotype: Mouse / IgG1 Background Information: Napsin is found in two isoforms, napsin A and B, with highly homologous nucleotide sequences (91.2%). Napsin A appears to be a functional proteinase, predominantly expressed in lung and kidney. Napsin B is transcribed exclusively in cells related to the immune system and lacks an in-frame stop codon and is believed to be a pseudogene.(PMID:12698189). Napsin A is superior to TTF-1 in distinguishing primary lung ACA from other carcinomas (except kidney), particularly primary lung small cell carcinoma, and primary thyroid carcinoma.(PMID:22288963).

 

 

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